What is a primary concern noted in cases of gender dysphoria?

In cases of gender dysphoria, a primary concern is the significant distress experienced regarding one's assigned gender. Individuals with gender dysphoria often feel a profound disconnect between their experienced or expressed gender and the gender they were assigned at birth, leading to emotional and psychological distress. This discomfort can manifest in various ways, such as anxiety, depression, or a strong desire to transition to a different gender. The DSM-5-TR emphasizes the importance of this distress as it affects the individual's overall functioning and well-being, making it a key marker for diagnosis and understanding of the condition. The recognition of this distress is crucial in guiding appropriate interventions and support for individuals experiencing gender dysphoria.