Which symptom is NOT a criterion for Major Depressive Disorder?

A feeling of grandiosity is indeed not a symptom associated with Major Depressive Disorder (MDD) as described in the DSM-5-TR. Instead, feelings of grandiosity are typically linked to manic or hypomanic episodes, which are characteristic of Bipolar Disorder. In contrast, the symptoms that define MDD include issues like insomnia or hypersomnia, significant changes in weight, and difficulties with concentration and decision-making. These symptoms point to the pervasive nature of low mood and cognitive impairment associated with depression, which is central to the disorder's diagnosis. Thus, the absence of grandiosity among the criteria helps distinguish MDD from mood disorders like Bipolar Disorder, where such elevated mood states can occur.